Resveratrol | Anti-Aging, Life Extenstion with Trans Resveratrol

Resveratrol

Resveratrol is a powerful antioxidant that is gaining in recognition and popularity as research information about its many health benefits grows. It is a key antioxidant in red wine, the skins of grapes, and other berries. Resveratrol is produced in some plants to help protect the plant from environmental stressors such as sun damage and fungal diseases. Similarly, the antioxidant power of resveratrol has been shown to help reduce the effects of aging in humans.

Resveratrol and Aging

Resveratrol is known for its potent antioxidant effect on the human body. This effect not only fights aging in skin and outward appearance; it also has been found to protect the body’s organs from the effects of aging. Specifically, resveratrol is proving to be very promising in improving cardiovascular health. In addition, research has shown resveratrol to influence gene expression. Gene expression in the tissues of the body change as animals and humans age. For example, there are at least 1,029 genes in the heart alone whose functions change with age. Consequently, the organ's function diminishes with age. One study performed on animals showed that low doses of resveratrol prevented age-related change in gene expression by 92 percent. This is exciting news as it reveals that heart function can be preserved to a great extent with the consumption of resveratrol.

Additionally, the study is encouraging because it shows the significant impact of resveratrol on health when taken in smaller, more realistic doses. Research has been clear that resveratrol is beneficial for heart health as well as the prevention of some cancers. However, most of the research performed has evaluated extremely large quantities of resveratrol in mice and other animals. The dosages were not realistic for daily human consumption. Recent research is indicating that smaller doses of resveratrol can also be extremely beneficial for health.

Caloric Restriction Effect of Resveratrol

Researchers have found that low doses of resveratrol can mimic the effects of what is known as caloric restriction. This means that consuming low doses of resveratrol can provide similar health benefits as those on diets with 20-30 percent fewer calories than a typical diet. Numerous studies have shown resveratrol to extend lifespan and thwart the effects of aging for this reason. Resveratrol’s ability to mimic caloric restriction promotes heart health and works to curb obesity, which improves the body’s overall health.

The French Paradox and Resveratrol

The French paradox study evaluated the health of the French in comparison to Americans. The study showed that people in France who consumed high fat diets similar to high fat American diets were less likely to die of heart-related problems than were Americans. People in France usually accompany each meal with a glass of red wine. It is believed that the resveratrol in the red wine protects people’s hearts and prolongs life. The French paradox study prompted the continued study of resveratrol. The results have been astounding.

• Adding resveratrol to the diet of yeast, fruit flies, worms, and a species of fish increased their life spans up to 70%, 29%, 24%, & 50% respectively.
• Fat related deaths dropped by 31% in obese mice who were fed resveratrol. In addition, obese mice given resveratrol performed significantly better in movement and agility tests than obese mice not fed resveratrol.
• Mice fed resveratrol had 100% more endurance than mice not fed resveratrol (i.e. they were able to run twice as far on a treadmill).
• Resveratrol inhibits blood platelet aggregation that can lead to dangerous clots, which can cause heart attacks and strokes.
• Resveratrol has been proven to fight cancer in vitro at all three stages; (1) initiation, (2) promotion, (&) progression.

Resveratrol Dosage and Side Effects

Research on resveratrol is extremely limited. At this point, no negative side effects have been noted concerning resveratrol. But it is important to remember that there is still very little research on resveratrol and humans. Pregnant or breastfeeding women should not take resveratrol for lack of research. Due to its potential anti-growth activity, children should not take resveratrol for lack research as well. Resveratrol can have a mild estrogenic activity. Therefore, people dealing with certain cancers should consult with their physician before taking resveratrol. It is also unclear how resveratrol could interfere with enzymes and other drugs. Always consult with your physician before taking any new medication or supplements.

The major benefit to taking resveratrol supplements is that you can achieve the health benefits of resveratrol without consuming alcohol, such as red wine. The recommended dosage of resveratrol is approximately 5 mg per kilogram — about 150 mg per day for the average adult.

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